When you think about chances it is easy to think about gambling. But also in science chances are important. Scientists use statistics to discover which theories are more likely then others. But the notion of chance always remains relatively abstract. What is a chance? And more important; what would you do if you knew the chance? Philosopher Jan Willem Romeijn studies the different types of chances that exist. Epidemiologist Edwin van de Heuvel explains what can can go wrong when you think you know the chance. Movement scientist Gert-Jan Pepping studied how you might be able to increase the chances that a team wins in a soccer penalty shootout.